ABSTRACT:A wide range of research uses patterns of genetic variation to infer genetic similarity between individuals, typically referred to as genetic ancestry. This research includes inference of human demographic history, understanding the genetic architecture of traits, and predicting disease risk. Researchers are not just structuring an intellectual inquiry when using genetic ancestry, they are also creating analytical frameworks with broader societal ramifications. This essay presents an ethics framework in the spirit of virtue ethics for these researchers: rather than focus on (...) rule following, the framework is designed to build researchers’ capacities to react to the ethical dimensions of their work. The authors identify one overarching principle of intellectual freedom and responsibility, noting that freedom in all its guises comes with responsibility, and they identify and define four principles that collectively uphold researchers’ intellectual responsibility: truthfulness, justice and fairness, anti-racism, and public beneficence. Researchers should bring their practices into alignment with these principles, and to aid this, the authors name three common ways research practices infringe these principles, suggest a step-by-step process for aligning research choices with the principles, provide rules of thumb for achieving alignment, and give a worked case. The essay concludes by identifying support needed by researchers to act in accord with the proposed framework. (shrink)

Shifts in the national cultural identity of the US have been reflected in shifts in the US’ dominant constitutional narratives. For the United States, “inter-legality” has been less a matter of dealing with alternative non-state legal narratives than of contending with constantly arising and competing narratives about the “correct” nature of the “official” legal order of the state. The US Supreme Court has claimed to have the “last word” in resolving these arguments but because that Court is so often sharply (...) divided and because the Court membership and the nature of its “last words” changes so often, where a significant element of the society seeks to advance its ideas and interests, it will often do so in legal and constitutional terms. As the national culture undergoes changes, a competing constitutional narrative may gain ground and even ultimately prevail, at least for a time, and achieve Supreme Court “endorsement” for its claims. (shrink)

The interpretation of the US Constitution by the Supreme Court of the US has often focused on conflicts arising from intense differences over the meaning attached to symbols including armbands, flags and banners; statues of the Ten Commandments and other religious symbols; depictions involving indecent images; and the conflicting perceptions of, and reactions to, “dirty” words. The symbols involved in these conflicts are essentially condensation symbols, and divisions over these decisions reflect cultural rifts that manifest themselves in the profoundly different (...) ways large groups of US citizens perceive images and words that evoke powerful emotional response. The Court has utilized a variety of doctrinal devices while engaging in the process of constitutional interpretation as it has struggled with these controversies in the context shaped by the broader culture that informs and constrains this process and by the elements within it that constantly struggle for validation. But the efficacy of its efforts remains questionable. (shrink)

The central project of the Critique of Pure Reason is to answer two sets of questions: What can we know and how can we know it? and What can't we know and why can't we know it? The essays in this collection are intended to help students read the Critique of Pure Reason with a greater understanding of its central themes and arguments, and with some awareness of important lines of criticism of those themes and arguments.

Mindfulness and compassion meditation are thought to cultivate prosocial behavior. However, the lack of diverse representation within both scientific and participant populations in contemplative neuroscience may limit generalizability and translation of prior findings. To address these issues, we propose a research framework calledIntersectional Neurosciencewhich adapts research procedures to be more inclusive of under-represented groups. Intersectional Neuroscience builds inclusive processes into research design using two main approaches: 1) community engagement with diverse participants, and 2) individualized multivariate neuroscience methods to accommodate neural (...) diversity. We tested the feasibility of this framework in partnership with a diverse U.S. meditation center (East Bay Meditation Center, Oakland, CA). Using focus group and community feedback, we adapted functional magnetic resonance imaging (fMRI) screening and recruitment procedures to be inclusive of participants from various under-represented groups, including racial and ethnic minorities, gender and sexual minorities, people with disabilities, neuropsychiatric disorders, and/or lower income. Using person-centered screening and study materials, we recruited and scanned 15 diverse meditators (80% racial/ethnic minorities, 53% gender and sexual minorities). The participants completed the EMBODY task – which applies individualized machine learning algorithms to fMRI data – to identify mental states during breath-focused meditation, a basic skill that stabilizes attention to support interoception and compassion. All 15 meditators’ unique brain patterns were recognized by machine learning algorithms significantly above chance levels. These individualized brain patterns were used to decode the internal focus of attention throughout a 10-min breath-focused meditation period, specific to each meditator. These data were used to compile individual-level attention profiles during meditation, such as the percentage time attending to the breath, mind wandering, or engaging in self-referential processing. This study provides feasibility of employing an intersectional neuroscience approach to include diverse participants and develop individualized neural metrics of meditation practice. Through inclusion of more under-represented groups while developing reciprocal partnerships, intersectional neuroscience turns the research process into an embodied form of social action. (shrink)

This book taps the best American thinkers to answer the essential American question: How do we sustain our experiment in government of, by, and for the people? Authored by an extraordinary and politically diverse roster of public officials, scholars, and educators, these chapters describe our nation's civic education problem, assess its causes, offer an agenda for reform, and explain the high stakes at risk if we fail.

The logics of the modal operators and of the quantifiers show striking analogies. The analogies are so extensive that, when a special class of entities (possible worlds) is postulated, natural and non-arbitrary translation procedures can be defined from the language with the modal operators into a purely quantificational one, under which the necessity and possibility operators translate into universal and existential quantifiers. In view of this I would be willing to classify the modal operators as ‘disguised’ quantifiers, and I think (...) that wholehearted acceptance of modal language should be considered to carry ontological commitment to something like possible worldsConsidered as two languages for describing the same subject matter, modal and purely quantificational languages show interesting differences. The operator variables of the purely quantificational languages give them more power than the modal languages, but at least some of the functions performed by the apparatus of operator variables are also performed, in a more primitive and less versatile way, by actuality operators in modal languages.A final note. Quine has written much on the inter-relations of quantifiers, identity, and the concept of existence. These, he holds, form a tightly knit conceptual system which has been evolved to a high point of perfection, but which might conceivably change yet further.29 He has also dropped hints about the possibility of a simpler, primitive or defective version of the system, in which the quantifiers are not backed up in their accustomed way by the concept of identity. He has dubbed the resulting concept a ‘pre-individuative’ concept of existence, or a concept of ‘entity without identity.’ What would a pre-individuative concept of existence be like? Quine has sometimes suggested that one might be embodied in the use of mass nouns, but the identity concept is used in connection with stuff as well as with things: “is that the same coffee that was in the cup last night?” I would submit that modality provides a better case. In view of the comparative weakness of modal languages, compared to the explicitly quantificational ones Quine takes as canonical, there is surely a sense in which the concept of existence embodied in that disguised existential quantifier, the possibility operator, is a defective one. And as we have seen, one of the differences between modal operators and explicit quantifiers is that modal operators cannot be joined with the identity predicate in the way quantifiers with operator variables can. Surely, then, there is a sense in which ordinary speech, as opposed to the metaphysical theorizing of a Leibniz or a David Lewis, conceives of possible worlds as entities without identity. (shrink)

Not the least admirable of the late David Lewis’s attributes was his disdain for technical terminology and jargon. His writings are a model demonstrating that, with skill and care, it is possible to discuss even the most mathematical aspects of logic and semantics in clear English prose, and with only a minimum of symbolism. The main text of Parts of Classes [1, hereafter: PoC], a 120-page essay on the foundations of set theory, follows Aristotle in using letters as variables, (...) and has a few dashes and ellipses where it mentions schemata, but is otherwise free of logical notation. The essential advantages of what Church called “the logistic method” do not depend on its typographical accidents!) It is only natural that writers following him have taken one of his expressive words and turned it into a technical term: he allowed ‘atomless gunk’ as a possible complication in the mereological analysis of things, and ‘gunk’ is now a technical term in mereology. Gunk is stuff every part of which contains further parts, stuff which can be divided endlessly without ever arriving at an indivisible atom. (shrink)

The question of truth is perhaps a perennial question of philosophy. Is truth “merely” epistemological, a function of contingent human practices and conventions, or should we adopt a stonger, metaphysical conception of truth along realist lines, understood as correspondence with objectively existing reality? In this paper I examine a famous debate in the analytic philosophy of language that hinges on the status of truth – specifically, the challenge to traditional or metaphysical realism posed by Hilary Putnam’s model-theoretic argument and the (...) “paradox” that David Lewis derived from it. In the end, I will argue that metaphysical realism is a theoretically excessive position with regards to truth, and that a pragmatic or epistemological understanding of realism is, in Putnam’s words, “all the realism we want or need.”. (shrink)

In a long and many-sided career, William Hasledine Pepys contributed significantly to the advancement of the chemical and physical sciences during the first half of the nineteenth century. As an original investigator he determined, in collaboration with William Allen, the composition of carbon dioxide, and the density of ammonia, and elucidated the chemical phenomena of respiration in man, animals, and plants. The success of these researches was largely due to the use of ingenious apparatus of his own invention and (...) design. In the field of experimental physics, he investigated several aspects of the recently discovered Voltaic electricity: his 'Voltaic coil', consisting of only two plates, but of very large dimensions, was particularly suited for investigating electromagnetic phenomena and was so used in Davy's researches. Pepys was one of the co-founders of the Mineralogical and Geological Societies, and was elected a Fellow of the Royal Society in 1808. As a prominent member of both the Royal and London Institutions, he held honorary office as Manager and Vice-President, contributing materially to the direction of the affairs of these bodies. Pepys was a friend of Humphry Davy and was acquainted with nearly all the leading scientists and medical men of the day. At the same time, he superintended a notable manufacture of surgical instruments in the City, and promoted by his active directorship the affairs of two public companies, both pioneers in their technological fields, namely the Imperial Continental Gas Association, which was active in introducing the new gas illumination to cities and towns across Europe, and the General Steam Navigation Company, which first maintained a regular passenger and cargo service to Continental ports by the exclusive use of steam-propelled vessels. Pepys' advice in scientific and technical matters was widely sought and freely given; he retained his mental powers to the end of his long life, fulfilling his professional commitments until a few days before his death. (shrink)

This volume collects for the first time in a single volume all of Kant's writings on religion and rational theology. These works were written during a period of conflict between Kant and the Prussian authorities over his religious teachings. His final statement of religion was made after the death of King Frederick William II in 1797. The historical context and progression of this conflict are charted in the general introduction to the volume and in the translators' introductions to particular (...) texts. All the translations are new with the exception of The Conflict of the Faculties, where the translation has been revised and re-edited to conform to the guidelines of the Cambridge Edition. As is standard with all the volumes in this edition, there are copious linguistic and explanatory notes, and a glossary of key terms. (shrink)

The twenty-sixth volume in the highly acclaimed Library of Living Philosophers series is devoted to the work of British philosopher of logic and metaphysician, P. F. Strawson. Following the Library of Living Philosophers series format, the volume contains an intellectual autobiography, twenty critical and descriptive essays by leading philosophers from around the world, Strawson's replies to the essays, and a bibliography of Strawson's works. Born in 1919, Strawson was a leading proponent of ordinary language philosophy. He is the author of (...) the early and extremely influential paper "On Referring" in which he criticized Russell's theory of definite descriptions. His most influential book, Individuals, helped to raise the status of metaphysics as a philosophical enterprise. Themes first addressed in this book continued to be of concern to him in his later work, including the possibility of objective knowledge, the subject-predicate distinction, the ontological status of persons, and the problem of individuation. Contributors to the book include: Ruth Garrett Millikan, Susan Haack, E. M. Adams, Panayot Butchvarov, Richard Behling, John McDowell, Simon Blackburn, Tadeusz Szubka, David Frederick Haight, Joseph S. Wu, Andrew G. Black, David Pears, Robert Boyd, Hilary Putnam, Paul F. Snowdon, Arindam Chakrabarti, Wenceslao J. Gonzalez, Ernest Sosa, Chung-M. Tse, John R. Searle, P. F. Strawson. (shrink)

The question of the role of theory in the determination of reference of theoretical terms continues to be a controversial one. In the present paper I assess a number of responses to this question (including variations on David Lewis’s appeal to Ramsification), before describing an alternative, epistemically oriented account of the reference-determination of such terms. The paper concludes by discussing some implications of the account for our understanding of both realism and such competitors of realism as constructive empiricism.

The Times Literary Supplement of Thursday, June 19, 1969 reports that "Mr. A. V. Miller has Just produced a new version of the Science of Logic which is intended to replace that of the American translators Johnston and Struthers issued in 1929. It is clearly a most painstaking piece of work, and. it certainly succeeds in presenting Hegel in an idiom which is intelligible, if not exactly elegant..." The work contains a foreword by J. N. Findlay of Yale University, and (...) was recently published by Allen & Unwin in Britain. It is available in this country through the Humanities Press, New York. The extensive T. L. S. article also reviews the tradition of Hegelian scholarship, particularly in England and France. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Controversy Between Schelling and Jacobi LEWIS S. FORD SCHELLING, ALONGWITH FICHTE, has suffered the fate of being labelled one of tIegel's predecessors. Richard Kroner provides the classic expression of this viewpoint in his monumental study, Von Kant bis Hegel, which examines Schelling's thought primarily for its contribution to Hegel's final synthesis.I In English we have Josiah Royce's sympathetic and lively account of Schelling's early romantic exuberance, regarded (...) as a transitional stage in the development of German idealism. 2 But this emphasis on the early ScheUing has led to an unfortunate neglect of his work subsequent to the break with Hegel in 1807. Schelling's romanticism, so ably documented by E. D. Hirsch, Jr., 3 can only be regarded as one phase in the total sweep of his thought, for, after the break with Hegel, Schelling produced at least three major works: the essay •ber das Wesen der menschlichen Freiheit,4 wrestling with the problem of evil and human freedom, the fragmentary Weltalter, 5 which in scope and dialectical intricacy should be compared with Hegel's Logic, and the Philosophie der Mythologie und Offenbarung, 6 furnishing a fundamental critique of the whole dialectical enterprise. Save for the essay on human freedom, however, none of these works were published during his lifetinm, as Schelling withdrew from the public eye after his controversies with Hegel and Jacobi. Thus the publishing histories of Schelling and Hegel are exactly reverse. Schelling rushed into print his early speculative gropings, while Hegel suppressed his/making the Ph~nomenologic des Geistes his first major publication. Then while Hegel's Logic and Encyclopedia were being publicly acclaimed, Schelling remained silent. This accident of history is largely responsible for the illusion that Schelling is the older of the two x (Tiibingen: J. C. B. Mohr, 1921-24),2 vols. 2The Spirit of Modern Philosophy (Boston: Houghton Mifflin, 1892), Lecture VI, 164-189. Wordsworth and ScheUing, A Typological Study of Romanticism (New Haven: Yale University Press, 1960),Yale Studies in English, Vol. CXLV. 4Friedrich Wilhelm Joseph yon Sehelling, Philosophische Untersuchungen i~berdas Wesen der menschlichen Freyheit und die damit zusaramenhdngenden Gegenstdnde, 1809. Reprinted in the Sdmmtliche Werke, Erste Abtheilung, VII. Band (Stuttgart und Augsburg: J. G. Cotta, 1856), 331-416. English translation by James Gutmann: Of Human Freedom (Chicago: Open Court, 1936). 5Three fragmentary versions of the Weltalter have been published. The Urfassungen of 1811 and 1813were edited by Manfrcd SehrSter and published as a separate Naehlassband to the M~nchener Jubildumsausgabe of the collected works: Die Weltalter, Fragmente (Munich: Biederstein, Leibniz, 1946). A later version is published in S.W. I: 8, pp. 195-344,which has been translated by Frederick de Wolfe Bolman, Jr. : The Ages of the World (NewYork: Columbia University Press, 1942). 6Philosophie der Mythologie is published in S.W. II: 1-2; Philosophie der Offenbarung in S.W. II: 3-4. These essays were first collected and published by Herman Nohl in Hegels theologische Jugendschriften (Tiibingen: 1907).T. M. Knox translated them into English, with an introduction by Richard Kroner: GeorgWilhelm Friedrich Hegel, Early Theological Writings (Chicago: University of Chicago Press, 1948). [75] 76 HISTORY OF PHILOSOPHY thinkers (actually he was five years Hegel's junior), who retired from the philosophical scene after making his contribution to the Hegelian synthesis. Paul Tillich's doctoral dissertations s and Ernst Cassirer's studies in post-Kantian thought 9 made serious inroads on this conception, yet the iIInsion persisted. Their insistence on the importance of the later Schelling has been brilliantly sustained by two recent studies: Horst Fuhrmans's Schellings Philosophie der Weltalter1~and Walter Schulz's Die Vollendung des deutschen Idealismus in der Spdtphilosophie Schellings, ~ and we may hope that the conventional estimate of Schelling will be drastically revised. Fuhrmans has demonstrated that the split between the early and the later Schelling must be placed in the year 1806 when he came in contact with Franz yon Bander in Munich, who encouraged him to delve deeper into the theological and cosmological ramifications of Jacob Boehme's thought. TM The reorientation this caused is apparent in the essay on human freedom, published in 1809, but it was not fully exploited until the... (shrink)

A significant ontological commitment is required to sustain metaphysical realism—the view that there is a single, objective way the world is—in order to defend it from common sense objections. This involves presupposing the existence of properties (or tropes, or universals) and relations between them which define the objective structure of the world. This paper explores the grounds for accepting this ontological assumption and examines a sceptical argument which questions whether, having assumed the world is objectively divided into fundamental properties, we (...) could ever know which properties these are. It then assesses the responses available to the metaphysical realist, arguing that the sceptical difficulty cannot merely be dismissed by means of another assumption in the manner of radical scepticism, as David Lewis suggests, but that the sceptic's argument might be defused by the non-question-begging success of some form of strong scientific realism which links the predicates of our scientific theories directly to the fundamental properties the world contains. It remains unclear however whether this widely accepted metaphysical theory can find principled philosophical support. (shrink)

Wisely, the authors begin this book by describing it as a polemic. They argue that most contemporary analytic metaphysics is a waste of time and resources since contemporary ‘neo-scholastic’ metaphysical theorizing cannot hope to attain objective truth given its penchant for making a priori claims about the nature of the world which are backed up by appeal to intuition. In engaging in this activity, metaphysicians have, the authors claim, abandoned hope of locating any interesting connection between their metaphysical pronouncements and (...) how our best empirical theories describe the world. Moreover, the success attained by empirical science just cannot be matched by metaphysical theorizing and so, faced with this asymmetry, empirical science wins: a priori metaphysical theorizing must give way to a naturalistic form of metaphysics, a positive account of which the authors attempt to elucidate in the second and third, rather lengthy chapters of the book.The first chapter consists of a statement of the authors’ negative view, a vigorous, sustained and sometimes withering attack upon contemporary a priori metaphysics. Most ire is reserved for those who indulge in what the authors call ‘pseudo-scientific metaphysics’; that is, those who pay lip service to keeping their metaphysical speculation in tune with physics, only to constrain their ontology in such a way that the entities and processes within it do not even play a role in current physical theory, or are in straightforward contradiction with it. Much philosophy of science and scientific metaphysics is too superficial and simplistic to deserve the name and bears more relation to ‘the philosophy of “A” Level chemistry’. The guilty in this respect include David Lewis, Jaegwon Kim, Jonathan Lowe, Donald Davidson, Jerry Fodor, Crawford Elder, Trenton Merricks among …. (shrink)

A 1971 paper by Roman Suszko, ‘Identity Connective and Modality’, claimed that a certain identity-free schema expressed the condition that there are at most two objects in the domain. Section 1 here gives that schema and enough of the background to this claim to explain Suszko’s own interest in it and related conditions—via non-Fregean logic, in which the objects in question are situations and the aim is to refrain from imposing this condition. Section 3 shows that the claim is false, (...) and suggests a diagnosis as to why it might have been made, in terms of quantifier scope distinctions as they bear on schematic formulations. In between, Section 2 discusses an issue brought up by this discussion but not involving the mistaken claim itself, and shows that Suszko was familiar with two different ways to set an upper or lower finite bound to the domain—a contrast which some contemporary readers may associate with David Lewis. (shrink)